Which form is zuranolone taken in?

• A. Intravenous solution
• B. Topical cream
• C. Oral pill
• D. Transdermal patch

Answer: (C)

Zuranolone is designed to be taken as an oral capsule because this route provides convenient, outpatient dosing with reliable, systemic absorption to reach the brain where it acts on GABA-A receptors. An oral pill allows controlled dosing and easy use outside a hospital setting, which fits how this drug is intended to be prescribed and used.

Intravenous delivery would require clinical supervision and is less practical for routine treatment. A topical cream or transdermal patch would face significant barriers to getting enough of the drug into the bloodstream—and even more into the brain—leading to unpredictable and insufficient CNS effects. Oral administration strikes the right balance between systemic exposure, patient convenience, and consistent pharmacokinetics for a CNS-acting steroid like zuranolone.