What is the release pattern of Mirena over the cycle?

• A. Higher initial release, then steadies off for a steady release rate throughout cycle.
• B. Constant release at a low rate throughout the cycle.
• C. Release rate fluctuates randomly during the cycle.
• D. No hormone release after placement.

Answer: (C)

Mirena releases levonorgestrel in a controlled pattern: there is a higher release rate right after placement, which then declines and settles into a relatively steady, low release rate for the remainder of its use. This means the device delivers a continuous amount over time rather than fluctuating randomly or stopping altogether. The higher initial burst plus a steady subsequent release best fits how Mirena functions.