The term 'sodium glucose cotransporter 2' implies the transporter co-transports which pair?

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Multiple Choice

The term 'sodium glucose cotransporter 2' implies the transporter co-transports which pair?

Explanation:
This concept hinges on recognizing that a sodium-glucose cotransporter is a symporter that moves Na+ and glucose together. The transporter uses the inward Na+ gradient, maintained by the Na+/K+-ATPase on the basolateral membrane, to bring glucose into the cell against its own gradient. That means the two substrates it carries are sodium and glucose. This is why inhibiting SGLT2 reduces glucose reabsorption in the kidney, causing more glucose to be excreted in urine. The other ions listed (potassium, calcium/phosphate, magnesium/sulfate) are not co-transported with glucose by this transporter.

This concept hinges on recognizing that a sodium-glucose cotransporter is a symporter that moves Na+ and glucose together. The transporter uses the inward Na+ gradient, maintained by the Na+/K+-ATPase on the basolateral membrane, to bring glucose into the cell against its own gradient. That means the two substrates it carries are sodium and glucose. This is why inhibiting SGLT2 reduces glucose reabsorption in the kidney, causing more glucose to be excreted in urine. The other ions listed (potassium, calcium/phosphate, magnesium/sulfate) are not co-transported with glucose by this transporter.

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