Isotretinoin is used to treat which condition?

• A. Psoriasis
• B. Rosacea
• C. Eczema
• D. Acne

Answer: (D)

Isotretinoin is used for severe acne because it tackles all the main acne-causing factors in one medication. It’s a powerful vitamin A derivative that shrinks the size and activity of the sebaceous glands, so sebum production drops dramatically. Less oil in the hair follicles means fewer clogged pores and fewer feeding sites for Propionibacterium acnes, which reduces both bacterial load and inflammation. It also helps normalize how skin cells shed within the follicles, preventing the formation of comedones. This combination can lead to long-lasting improvement after a single course, which is why isotretinoin is reserved for severe or treatment-resistant acne rather than conditions like psoriasis, eczema, or rosacea, which are managed with other therapies. Be aware that isotretinoin carries serious teratogenic risks and requires careful monitoring and contraception in patients of childbearing potential.