Does tafamidis cure ATTR?

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Multiple Choice

Does tafamidis cure ATTR?

Explanation:
Tafamidis lowers the pace of disease by stabilizing the transthyretin tetramer, preventing it from breaking apart into misfolded monomers that form amyloid. This slows the formation of new amyloid and can help stabilize or modestly improve symptoms for some patients. But it does not remove or reverse existing amyloid deposits, and it does not cure the disease. So the statement that tafamidis cures ATTR is not correct. It also does not accelerate progression. The best summary is that tafamidis slows the disease but is not curative.

Tafamidis lowers the pace of disease by stabilizing the transthyretin tetramer, preventing it from breaking apart into misfolded monomers that form amyloid. This slows the formation of new amyloid and can help stabilize or modestly improve symptoms for some patients. But it does not remove or reverse existing amyloid deposits, and it does not cure the disease. So the statement that tafamidis cures ATTR is not correct. It also does not accelerate progression. The best summary is that tafamidis slows the disease but is not curative.

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