Does Ocrelizumab cure MS?

• A. Yes
• B. No
• C. Only in some patients
• D. It depends on the subtype

Answer: (B)

Understanding the question hinges on the difference between a cure and a disease-modifying therapy. Ocrelizumab targets CD20-positive B cells to dampen the autoimmune attack on myelin, which reduces relapse rates and slows disability progression in both relapsing-remitting MS and primary progressive MS. This proves its effectiveness at controlling disease activity, but it does not eradicate MS or permanently restore lost neurological function. MS remains a chronic condition that can reactivate if therapy is stopped, and no treatment has been proven to cure the disease. So, while ocrelizumab can significantly reduce activity and progression, it is not a cure.