Allopregnanolone targets which receptor?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the Pharmacology Presentation Drugs Test. Delve into flashcards and multiple choice questions with hints and explanations. Gear up for examination success!

Multiple Choice

Allopregnanolone targets which receptor?

Explanation:
Allopregnanolone acts as a neurosteroid that potentiates GABA-A receptor activity. It binds to an allosteric site on the GABA-A receptor and enhances the effect of GABA, increasing chloride influx, which hyperpolarizes neurons and strengthens inhibitory signaling. This mechanism produces sedative, anxiolytic, and anticonvulsant effects. It does not target NMDA receptors, dopamine D2 receptors, or serotonin 5-HT2A receptors, which belong to different neurotransmitter systems. The take-home is that allopregnanolone’s main action is to boost GABA-A–mediated inhibition.

Allopregnanolone acts as a neurosteroid that potentiates GABA-A receptor activity. It binds to an allosteric site on the GABA-A receptor and enhances the effect of GABA, increasing chloride influx, which hyperpolarizes neurons and strengthens inhibitory signaling. This mechanism produces sedative, anxiolytic, and anticonvulsant effects. It does not target NMDA receptors, dopamine D2 receptors, or serotonin 5-HT2A receptors, which belong to different neurotransmitter systems. The take-home is that allopregnanolone’s main action is to boost GABA-A–mediated inhibition.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy